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Estrone O-sulfamate
CAS No. 148672-09-7
Estrone O-sulfamate( —— )
Catalog No. M36460 CAS No. 148672-09-7
Estrone O-sulfamate (Estrone 3-O-sulfamate) is a potent inhibitor of steroid sulfatase (STS), showing IC50 values of 18 nM as a placental microsomal inhibitor (P.M.) and 0.83 nM in MCF-7 cells.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 499 | Get Quote |
|
| 5MG | 747 | Get Quote |
|
| 10MG | 928 | Get Quote |
|
| 25MG | 1178 | Get Quote |
|
| 50MG | 1500 | Get Quote |
|
| 100MG | 1782 | Get Quote |
|
| 200MG | 2511 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
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Product NameEstrone O-sulfamate
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NoteResearch use only, not for human use.
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Brief DescriptionEstrone O-sulfamate (Estrone 3-O-sulfamate) is a potent inhibitor of steroid sulfatase (STS), showing IC50 values of 18 nM as a placental microsomal inhibitor (P.M.) and 0.83 nM in MCF-7 cells.
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DescriptionEstrone O-sulfamate (Estrone 3-O-sulfamate) is a potent steroid sulfatase (STS) inhibitor. Estrone O-sulfamate has inhibitory activity for STS in a placental microsomes (P.M.) preparation and in MCF-7 cells with IC50 values of 18 nM and 0.83 nM, respectively. Estrone O-sulfamate can be used for the research of cancer.
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In VitroEstrone O-sulfamate (Estrone 3-O-sulfamate) has inhibitory activity for STS in a placental microsomes (P.M.) preparation and in MCF-7 cells with IC50 values of 18 nM and 0.83 nM, respectively.
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number148672-09-7
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Formula Weight349.44
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Molecular FormulaC18H23NO4S
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Purity>98% (HPLC)
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Solubility——
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SMILESC[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(OS(N)(=O)=O)=CC4)(CC1)[H])[H])(CCC2=O)[H]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. L W Lawrence Woo, et al. Synthesis and evaluation of analogues of estrone-3-O-sulfamate as potent steroid sulfatase inhibitors. Bioorg Med Chem. 2012 Apr 15;20(8):2506-19.?
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