H2-Gamendazole( —— )

Catalog No. M36435 CAS No. 877768-84-8

H2-Gamendazole is a novel compound for spermatogenesis inhibition and cancer therapy as an inhibitor of heat shock proteins and/or elongation factor 1 alpha, and is an Hsp90 regulator.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	215	In Stock
5MG	190	In Stock
10MG	283	In Stock
25MG	504	In Stock
50MG	663	In Stock
100MG	910	In Stock
200MG	1200	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

H2-Gamendazole
Note

Research use only, not for human use.
Brief Description

H2-Gamendazole is a novel compound for spermatogenesis inhibition and cancer therapy as an inhibitor of heat shock proteins and/or elongation factor 1 alpha, and is an Hsp90 regulator.
Description

H2-Gamendazole is a derivative of Lonidamine that reduces cyst formation in polycystic kidney disease and is used in autosomal dominant polycystic kidney disease research.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Cytoskeleton/Cell Adhesion Molecules
Target

HSP
Recptor

HSP
Research Area

——
Indication

——

Chemical Information

CAS Number

877768-84-8
Formula Weight

417.21
Molecular Formula

C18H13Cl2F3N2O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 125 mg/mL (299.61 mM; Ultrasonic (<60°C)
SMILES

C(N1C=2C(C(CCC(O)=O)=N1)=CC=C(C(F)(F)F)C2)C3=C(Cl)C=C(Cl)C=C3
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Shirin V Sundar, et al. The lonidamine derivative H2-gamendazole reduces cyst formation in polycystic kidney disease. Am J Physiol Renal Physiol. 2022 Oct 1;323(4):F492-F506.??

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