BI-2493( —— )

Catalog No. M36424 CAS No. 2937344-16-4

COA

Datasheet

HNMR

HPLC

MSDS

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Product Name

BI-2493
Note

Research use only, not for human use.
Brief Description

BI-2493 is a highly selective pan-KRAS inhibitor and structural analog of BI-2865.BI-2493 exhibits antitumor activity and inhibits tumor cell growth and can be used in the study of cancerous diseases.
Description

BI-2493 is a structural analogue of BI-2865 and a highly selective pan-KRAS inhibitor. BI-2493 can attenuate tumor growth. BI-2493 can be used for cancer iseases research.
In Vitro

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In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

Kras
Research Area

——
Indication

——

CAS Number

2937344-16-4
Formula Weight

461.58
Molecular Formula

C24H27N7OS
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (108.32 mM; Ultrasonic )
SMILES

C(#N)C=1C=2[C@@]3(C4=C(C(=NO4)C5=NC(=NC=C5)N6[C@@H](C)CNCC6)CCC3)CCCC2SC1N
Chemical Name

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1. Kim D, et al. Pan-KRAS inhibitor disables oncogenic signalling and tumour growth. Nature. 2023 Jul;619(7968):160-166.?

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