Antibacterial agent 125

CAS No. 1274611-43-6

Antibacterial agent 125( —— )

Catalog No. M36413 CAS No. 1274611-43-6

Antibacterial Agent 125 exhibits potent antimicrobial activity against clinically relevant Gram-positive pathogens, displaying Minimum Inhibitory Concentration (MIC) 50 values ranging from 0.25 to 8 μM. It is suitable for researching antimicrobial resistance.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 41 In Stock
5MG 37 In Stock
10MG 61 In Stock
25MG 122 In Stock
50MG 198 In Stock
100MG 305 In Stock
200MG Get Quote In Stock
500MG 733 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Antibacterial agent 125
  • Note
    Research use only, not for human use.
  • Brief Description
    Antibacterial Agent 125 exhibits potent antimicrobial activity against clinically relevant Gram-positive pathogens, displaying Minimum Inhibitory Concentration (MIC) 50 values ranging from 0.25 to 8 μM. It is suitable for researching antimicrobial resistance.
  • Description
    Antibacterial agent 125 is an antibacterial agent. Antibacterial agent 125 has a potent antimicrobial activity against clinically relevant Gram-positive pathogens with MIC50 values range from 0.25 - 8 μM. Antibacterial agent 125 can be used for the research of antimicrobial resistance.
  • In Vitro
    Antibacterial agent 125 has activity against clinically relevant Gram-positive pathogens with MIC50 values from 0.25-8 μM.Antibacterial agent 125 has inhibitory activity against methicillin-resistant Staphylococcus aureus strain without showing cytotoxicity in human cells.Antibacterial agent 125 has high metabolic stability and excellent safety profile. Antibacterial agent 125 not induces resistance after ten passages and has a moderate ability to inhibit the biofilm formation.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Antibacterial
  • Recptor
    Antibacterial
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1274611-43-6
  • Formula Weight
    270.71
  • Molecular Formula
    C15H11ClN2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (923.50 mM; Ultrasonic (<60°C)
  • SMILES
    N(C(CC1=CC(Cl)=CC=C1)=O)C2=CC=C(C#N)C=C2
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Francesca Brunelli, et al. Isocyanides in med chem: A scaffold hopping approach for the identification of novel 4-isocyanophenylamides as potent antibacterial agents against methicillin-resistant Staphylococcusaureus. Eur J Med Chem. 2022 Nov 26;246:114950. ?
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