GTP-14564

CAS No. 34823-86-4

GTP-14564( —— )

Catalog No. M36386 CAS No. 34823-86-4

GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 32 In Stock
5MG 56 In Stock
10MG 102 In Stock
25MG 207 In Stock
50MG 323 In Stock
100MG 465 In Stock
200MG 641 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    GTP-14564
  • Note
    Research use only, not for human use.
  • Brief Description
    GTP-14564 is a novel tyrosine kinase inhibitor that also inhibits wt-FLT3 and ITD-FLT3.
  • Description
    GTP-14564 is a tyrosine kinase inhibitor targeting to internal tandem duplication (ITD) and FLT3. GTP-14564 inhibits FLT3 ligand-dependent growth in Ba/F3 leukemia cells.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Proteasome/Ubiquitin
  • Target
    Tyrosinase
  • Recptor
    Tyrosine Kinases | FLT
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    34823-86-4
  • Formula Weight
    234.25
  • Molecular Formula
    C15H10N2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 125 mg/mL (533.62 mM; Ultrasonic (<60°C)
  • SMILES
    C12=C(C=3C(O1)=CC=CC3)NN=C2C4=CC=CC=C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Murata K, et al. Selective cytotoxic mechanism of GTP-14564, a novel tyrosine kinase inhibitor in leukemia cells expressing a constitutively active Fms-like tyrosine kinase 3 (FLT3). J Biol Chem. 2003 Aug 29;278(35):32892-8.?
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