Cart
sales@molnova.com
Simmitecan hydrochloride
CAS No. 1247847-78-4
Simmitecan hydrochloride( —— )
Catalog No. M36364 CAS No. 1247847-78-4
Simmitecan hydrochloride is a camptothecin derivative, a topoisomerase I inhibitor with anticancer activity, which can be used to study is solid tumors.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 1216 | In Stock |
|
| 25MG | 2442 | In Stock |
|
| 50MG | 3143 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameSimmitecan hydrochloride
-
NoteResearch use only, not for human use.
-
Brief DescriptionSimmitecan hydrochloride is a camptothecin derivative, a topoisomerase I inhibitor with anticancer activity, which can be used to study is solid tumors.
-
DescriptionSimmitecan hydrochloride, a 9-substituted lipophilic Camptothecin (HY-16560) derivative, is a potent topoisomerase I inhibitor. Simmitecan hydrochloride is an anticancer agent.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCell Cycle/DNA Damage
-
TargetTopoisomerase
-
RecptorTopoisomerase
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1247847-78-4
-
Formula Weight635.15
-
Molecular FormulaC34H39ClN4O6
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESO=C1N2C(C=3C(C2)=CC=4C(N3)=CC=C(OC(=O)N5CCC(CC5)N6CCCCC6)C4CC=C)=CC7=C1COC(=O)[C@@]7(CC)O.Cl
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Rini B, et al. A phase I/II study of lenalidomide in combination with sunitinib in patients with advanced or metastatic renal cell carcinoma. Ann Oncol. 2014 Sep;25(9):1794-1799. ?
molnova catalog
related products
-
Exatecan Mesylate
Exatecan Mesylate is a DNA topoisomerase I inhibitor (IC50: 2.2 μM, 0.975 μg/mL).Exatecan Mesylate (DX-8951f) significantly inhibits the proliferation of several cancer cell lines, with mean GI50s of 2.02 ng/mL, 2.92 ng/mL, 1.53 ng/mL, and 0.877 ng/mL for breast cancer cells, colon cancer cells, stomach cancer cells and lung cancer cells, respectively.
-
N-Acetyl-D-Glucosami...
N-acetyl-D-Glucosamine (GlcNAc) is a monosaccharide derivative of glucose. It is released by the action of O-GlcNAcase, in mammalian systems from proteins that have been post-translationally modified with O-GlcNAc.
-
10-Hydroxycampotheci...
10-Hydroxycamptothecin is a DNA topoisomerase I inhibitor utilized as a clinical therapy agent against hepatoma.
