PA3552-IN-1( —— )

Catalog No. M36072 CAS No. 1008121-12-7

PA3552-IN-1 is an antibiotic adjuvant that can reduce the expression of PA3552 and restore the sensitivity of MDR Pseudomonas aeruginosa DK2 strain to Polymyxin B.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	28	In Stock
10MG	39	In Stock
25MG	79	In Stock
50MG	128	In Stock
100MG	194	In Stock
200MG	274	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

PA3552-IN-1
Note

Research use only, not for human use.
Brief Description

PA3552-IN-1 is an antibiotic adjuvant that can reduce the expression of PA3552 and restore the sensitivity of MDR Pseudomonas aeruginosa DK2 strain to Polymyxin B.
Description

PA3552-IN-1 (compound 15) is an antibiotic adjuvant that restores sensitivity of MDR P. aeruginosa DK2 strain to Polymyxin B. PA3552-IN-1 can reduce PA3552 expression.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

GPCR/G Protein
Target

Antibacterial
Recptor

Antibacterial
Research Area

——
Indication

——

Chemical Information

CAS Number

1008121-12-7
Formula Weight

310.67
Molecular Formula

C13H8ClFN2O4
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : ≥ 13.89 mg/mL (44.71 mM)
SMILES

Oc1ccc(F)cc1C(=O)Nc1ccc(cc1Cl)[N+]([O-])=O
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Lu T, et, al. Novel niclosamide-derived adjuvants elevating the efficacy of polymyxin B against MDR Pseudomonas aeruginosa DK2. Eur J Med Chem. 2022 Jun 5;236:114318.?

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