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Home - Products - Cell Cycle/DNA Damage - HDAC - HDAC-IN-52

HDAC-IN-52

CAS No. 2075787-77-6

HDAC-IN-52( —— )

Catalog No. M36045 CAS No. 2075787-77-6

HDAC-IN-52, a pyridine-containing HDAC inhibitor, effectively inhibits HDAC1, HDAC2, HDAC3, and HDAC10 with IC50 values of 0.189, 0.227, 0.440, and 0.446 μM, respectively.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 179 In Stock
5MG 157 In Stock
10MG 234 In Stock
25MG 356 In Stock
50MG 476 In Stock
100MG 644 In Stock
200MG 866 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    HDAC-IN-52
  • Note
    Research use only, not for human use.
  • Brief Description
    HDAC-IN-52, a pyridine-containing HDAC inhibitor, effectively inhibits HDAC1, HDAC2, HDAC3, and HDAC10 with IC50 values of 0.189, 0.227, 0.440, and 0.446 μM, respectively.
  • Description
    HDAC-IN-52 is a pyridine-containing HDAC inhibitor, with IC50s of 0.189, 0.227, 0.440 and 0.446 μM for HDAC1, HDAC2, HDAC3, and HDAC10, respectively. HDAC-IN-52 can be used for the research of cancer.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Cell Cycle/DNA Damage
  • Target
    HDAC
  • Recptor
    HDAC
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2075787-77-6
  • Formula Weight
    396.44
  • Molecular Formula
    C24H20N4O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(C(NC=1C=CC(C(NC2=C(N)C=CC=C2)=O)=NC1)=O)C3=CC4=C(C=C3)C=CC=C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Bello ED, et, al. Novel pyridine-containing histone deacetylase inhibitors strongly arrest proliferation, induce apoptosis and modulate miRNAs in cancer cells. Eur J Med Chem. 2022 Dec 15;247:115022.?
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