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VT104
CAS No. 2417718-25-1
VT104( —— )
Catalog No. M36039 CAS No. 2417718-25-1
VT104 is a potent and orally active YAP/TAZ inhibitor for cancer research. VT104 blocks palmitoylation of endogenous TEAD1 and TEAD3 proteins.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 109 | In Stock |
|
| 5MG | 242 | In Stock |
|
| 10MG | 394 | In Stock |
|
| 25MG | 619 | In Stock |
|
| 50MG | 869 | In Stock |
|
| 100MG | 1143 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameVT104
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NoteResearch use only, not for human use.
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Brief DescriptionVT104 is a potent and orally active YAP/TAZ inhibitor for cancer research. VT104 blocks palmitoylation of endogenous TEAD1 and TEAD3 proteins.
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DescriptionVT104 is a potent and orally active YAP/TAZ inhibitor. VT104 prevents palmitoylation of endogenous TEAD1 and TEAD3 proteins. VT104 can be used in research of cancer.
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In Vitro——
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In VivoAnimal Model:NCI-H226-tumor bearing mice Dosage:0.3, 1, and 3 mg/kg Administration:Oral administration Result:Blocked NCI-H226 tumor growth in mice in dose-dependent manner.
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorYAP
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Research Area——
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Indication——
Chemical Information
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CAS Number2417718-25-1
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Formula Weight420.43
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Molecular FormulaC25H19F3N2O
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (237.85 mM; Ultrasonic )
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SMILESC[C@H](NC(=O)c1ccc2c(cccc2c1)-c1ccc(cc1)C(F)(F)F)c1ccccn1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Tang TT, et, al. Small Molecule Inhibitors of TEAD Auto-palmitoylation Selectively Inhibit Proliferation and Tumor Growth of NF2-deficient Mesothelioma. Mol Cancer Ther. 2021 Jun;20(6):986-998.?
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