ISRIB-A15

CAS No. 1628478-12-5

ISRIB-A15( —— )

Catalog No. M35963 CAS No. 1628478-12-5

ISRIB-A15 (ISR-IN-2) is an potent inhibitor of the integrated stress response with an EC50 of 0.8 nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 92 In Stock
10MG 151 In Stock
25MG 242 In Stock
50MG 384 In Stock
100MG 575 In Stock
200MG Get Quote In Stock
500MG 1237 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ISRIB-A15
  • Note
    Research use only, not for human use.
  • Brief Description
    ISRIB-A15 (ISR-IN-2) is an potent inhibitor of the integrated stress response with an EC50 of 0.8 nM.
  • Description
    ISR-IN-2 (Compound 47) is an inhibitor of the integrated stress response (EC50: 0.8 nM).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1628478-12-5
  • Formula Weight
    520.23
  • Molecular Formula
    C22H22Cl4N2O4
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 2.5 mg/mL (4.81 mM; Ultrasonic (<60°C)
  • SMILES
    Clc1ccc(OCC(=O)N[C@H]2CC[C@@H](CC2)NC(=O)COc2ccc(Cl)c(Cl)c2)cc1Cl
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hearn BR, et al. Structure-Activity Studies of Bis-O-Arylglycolamides: Inhibitors of the Integrated Stress Response. ChemMedChem. 2016 Apr 19;11(8):870-80. ?
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