CB2R/FAAH?modulator-2

Research use only, not for human use.

CB2R/FAAH modulator-2 (compound 26) is a dual modulator targeting CB2R and FAAH, acting as a CB2R agonist (Ki = 10.8 nM) and FAAH inhibitor (IC50 = 6.2 μM), with a Ki value of 152.9 nM for CB1R.

CB2R/FAAH modulator-2 (compound 26) is a dual targeting modulator that acts as a CB2R agonist and FAAH inhibitor. The Ki values for CB2R/FAAH modulator-2 are 10.8 and 152.9 nM for CB2R and CB1R, respectively, and the IC50 value for FAAH is 6.2 μM. CB2R/FAAH modulator-2 can be used in studies related to cancer, deleterious inflammatory cascades occurring in neurodegenerative diseases, and COVID-19 infection.

CB2R/FAAH modulator-2 (compound 26)(10 μM) reduces the production of the pro-inflammatory cytokines TNFα, IFN-γ, IL-1β and IL6 in unstimulated monocytes and macrophages.

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GPCR/G Protein

Cannabinoid Receptor

Cannabinoid Receptor | FAAH

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2876918-68-0

367.52

C24H33NO2

>98% (HPLC)

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N(C(=O)C1=C(OCC2CCCCC2)C=CC=C1)C34CC5CC(C3)CC(C4)C5

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(-20℃)

With Ice Pack

≥ 2 years