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Dynamin IN-2
CAS No. 1345853-49-7
Dynamin IN-2( —— )
Catalog No. M35809 CAS No. 1345853-49-7
Dynamin IN-2 (compound 43) is a Wiskostatin analogue. Dynamin IN-2 is a potent dynamin inhibitor (dynamin I GTPase, IC50= 1.0 μM). Dynamin IN-2 blocks clathrin mediated endocytosis (CME) (IC50= 9.5 μM).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 341 | In Stock |
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| 5MG | 332 | In Stock |
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| 10MG | 440 | In Stock |
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| 25MG | 667 | In Stock |
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| 50MG | 876 | In Stock |
|
| 100MG | 1172 | In Stock |
|
| 200MG | 1562 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameDynamin IN-2
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NoteResearch use only, not for human use.
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Brief DescriptionDynamin IN-2 (compound 43) is a Wiskostatin analogue. Dynamin IN-2 is a potent dynamin inhibitor (dynamin I GTPase, IC50= 1.0 μM). Dynamin IN-2 blocks clathrin mediated endocytosis (CME) (IC50= 9.5 μM).
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DescriptionDynamin IN-2 (compound 43), a Wiskostatin (HY-12534) analogue, is a potent dynamin inhibitor, with an IC50 of 1.0 μM for dynamin I GTPase. Dynamin IN-2 also blocks clathrin mediated endocytosis (CME), with an IC50 of 9.5 μM.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCytoskeleton/Cell Adhesion Molecules
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TargetDynamin
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RecptorDynamin
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Research Area——
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Indication——
Chemical Information
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CAS Number1345853-49-7
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Formula Weight364.87
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Molecular FormulaC22H21ClN2O
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Purity>98% (HPLC)
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Solubility——
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SMILESC(C(CNCC1=CC=C(Cl)C=C1)O)N2C=3C(C=4C2=CC=CC4)=CC=CC3
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Cossar PJ, et al. Wiskostatin and other carbazole scaffolds as off target inhibitors of dynamin I GTPase activity and endocytosis. Eur J Med Chem. 2022 Dec 15;247:115001.?
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