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AZD0780

CAS No. 2455427-91-3

AZD0780( —— )

Catalog No. M35805 CAS No. 2455427-91-3

AZD0780 (EX-A6975) is an oral small molecule PCSK9 inhibitor being developed by AstraZeneca as a first-in-class treatment for patients with dyslipidemia that is uncontrolled with statins alone.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 141 Get Quote
5MG 217 Get Quote
10MG 353 Get Quote
25MG 579 Get Quote
50MG 824 Get Quote
100MG 1098 Get Quote
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Biological Information

  • Product Name
    AZD0780
  • Note
    Research use only, not for human use.
  • Brief Description
    AZD0780 (EX-A6975) is an oral small molecule PCSK9 inhibitor being developed by AstraZeneca as a first-in-class treatment for patients with dyslipidemia that is uncontrolled with statins alone.
  • Description
    PCSK9-IN-12 is a heteroaryl compound. PCSK9-IN-12has bind affinity for PCSK9with a Kd value of ＜200 nM. PCSK9-IN-12 can be used for the research of cholesterol metabolism.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2455427-91-3
  • Formula Weight
    414.41
  • Molecular Formula
    C20H20F2N6O2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 100 mg/mL (241.31 mM; Ultrasonic )
  • SMILES
    FC(F)Oc1cnc(N[C@H]2CC[C@@H](C2)Nc2ccc(cn2)-n2ccccc2=O)nc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Michael H. Serrano-Wu, et al. Pcsk9 inhibitors and methods of use thereof. Patent. WO2020150474A1.
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