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AZD0780
CAS No. 2455427-91-3
AZD0780( —— )
Catalog No. M35805 CAS No. 2455427-91-3
AZD0780 (EX-A6975) is an oral small molecule PCSK9 inhibitor being developed by AstraZeneca as a first-in-class treatment for patients with dyslipidemia that is uncontrolled with statins alone.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 167 | In Stock |
|
| 5MG | 150 | In Stock |
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| 10MG | 236 | In Stock |
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| 25MG | 377 | In Stock |
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| 50MG | 529 | In Stock |
|
| 100MG | 731 | In Stock |
|
| 200MG | 1014 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameAZD0780
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NoteResearch use only, not for human use.
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Brief DescriptionAZD0780 (EX-A6975) is an oral small molecule PCSK9 inhibitor being developed by AstraZeneca as a first-in-class treatment for patients with dyslipidemia that is uncontrolled with statins alone.
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DescriptionPCSK9-IN-12 is a heteroaryl compound. PCSK9-IN-12has bind affinity for PCSK9with a Kd value of ＜200 nM. PCSK9-IN-12 can be used for the research of cholesterol metabolism.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorOthers
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Research Area——
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Indication——
Chemical Information
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CAS Number2455427-91-3
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Formula Weight414.41
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Molecular FormulaC20H20F2N6O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (241.31 mM; Ultrasonic )
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SMILESFC(F)Oc1cnc(N[C@H]2CC[C@@H](C2)Nc2ccc(cn2)-n2ccccc2=O)nc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Michael H. Serrano-Wu, et al. Pcsk9 inhibitors and methods of use thereof. Patent. WO2020150474A1.
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