Cart
sales@molnova.com
(+)-JNJ-A07
CAS No. 2135640-93-4
(+)-JNJ-A07( —— )
Catalog No. M35764 CAS No. 2135640-93-4
(+)-JNJ-A07 is a pan-serotypic dengue virus inhibitor that targets NS3-NS4B interaction with high potency. (+)-JNJ-A07 has antiviral activity and can be used to study dengue virus infections.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 188 | In Stock |
|
| 5MG | 150 | In Stock |
|
| 10MG | 236 | In Stock |
|
| 25MG | 377 | In Stock |
|
| 50MG | 529 | In Stock |
|
| 100MG | 731 | In Stock |
|
| 200MG | 1004 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name(+)-JNJ-A07
-
NoteResearch use only, not for human use.
-
Brief Description(+)-JNJ-A07 is a pan-serotypic dengue virus inhibitor that targets NS3-NS4B interaction with high potency. (+)-JNJ-A07 has antiviral activity and can be used to study dengue virus infections.
-
Description(+)-JNJ-A07 is a highly potent, orally active pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction. (+)-JNJ-A07 exerts nanomolar to picomolar activity against a panel of 21 clinical isolates. (+)-JNJ-A07 has a favourable pharmacokinetic profile that results in outstanding efficacy against dengue virus infection in mouse infection models.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorVirus Protease
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2135640-93-4
-
Formula Weight578.96
-
Molecular FormulaC28H26ClF3N2O6
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (172.72 mM; Ultrasonic )
-
SMILESC(C(NC1=CC(OCCCC(O)=O)=CC(OC)=C1)C2=CC=C(Cl)C=C2)(=O)N3C=4C(CC3)=CC=C(OC(F)(F)F)C4
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Kaptein SJF, et al. A pan-serotype dengue virus inhibitor targeting the NS3-NS4B interaction [published correction appears in Nature. 2021 Nov;599(7883):E2]. Nature. 2021;598(7881):504-509. ?
molnova catalog
related products
-
C-terminal Proghreli...
C-terminal Proghrelin Isoform Peptide, mouse
-
Gehuain
Gehuain
-
Trans-Zeatin Ribosid...
Zeatin Riboside is the most active and ubiquitous form of the naturally occurring cytokinins that promote cell division, stimulate shoot proliferation, inhibit root formation, slow the aging process, and activate gene expression and metabolic activity.
