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Iruplinalkib
CAS No. 1854943-32-0
Iruplinalkib( —— )
Catalog No. M35759 CAS No. 1854943-32-0
Iruplinalkib (WX-0593) is an orally active, selective and potent ALK and ROS1 tyrosine kinase inhibitor with anticancer activity for use in the study of non-small cell lung cancer.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 117 | In Stock |
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| 10MG | 188 | In Stock |
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| 25MG | 411 | In Stock |
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| 50MG | 553 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
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Biological Information
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Product NameIruplinalkib
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NoteResearch use only, not for human use.
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Brief DescriptionIruplinalkib (WX-0593) is an orally active, selective and potent ALK and ROS1 tyrosine kinase inhibitor with anticancer activity for use in the study of non-small cell lung cancer.
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DescriptionIruplinalkib (WX-0593) is a potent, selective, and orally active inhibitor of ALK and ROS1 tyrosine kinase. Iruplinalkib (WX-0593) shows favorable safety and promising antitumor activity in advanced NSCLC with ALK or ROS1 rearrangement.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAngiogenesis
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TargetALK
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RecptorALK | ROS Kinase
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Research Area——
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Indication——
Chemical Information
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CAS Number1854943-32-0
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Formula Weight569.08
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Molecular FormulaC29H38ClN6O2P
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 10 mg/mL (17.57 mM; Ultrasonic (<60°C)
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SMILESO=P(C=1C=CC=CC1NC2=NC(=NC=C2Cl)NC3=CC=C(C=C3OC)N4CCC5(CC4)CCN(C)CC5)(C)C
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Shi Y, et al. Safety and activity of WX-0593 (Iruplinalkib) in patients with ALK- or ROS1-rearranged advanced non-small cell lung cancer: a phase 1 dose-escalation and dose-expansion trial. Signal Transduct Target Ther. 2022;7(1):25. ?
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