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DENV-IN-5

CAS No. 2375781-06-7

DENV-IN-5( —— )

Catalog No. M35702 CAS No. 2375781-06-7

Denv-in-5 is an effective and selective dengue virus (DENV) inhibitor with EC50 values of 1.47, 9.23, 7.08, 8.91 μM for denV-I-IV and 0.1512 μM for HIV-1IIIB.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	947	In Stock
5MG	1017	In Stock
10MG	1359	In Stock
25MG	1995	In Stock
50MG	2399	In Stock
100MG	3162	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

DENV-IN-5
Note

Research use only, not for human use.
Brief Description

Denv-in-5 is an effective and selective dengue virus (DENV) inhibitor with EC50 values of 1.47, 9.23, 7.08, 8.91 μM for denV-I-IV and 0.1512 μM for HIV-1IIIB.
Description

DENV-IN-5 (Compound 4b) is a dengue virus (DENV) inhibitor with EC50s of 1.47, 9.23, 7.08 and 8.91 μM against DENV-I ～ IV replication, respectively. DENV-IN-5 also inhibits HIV-1IIIB strain with an EC50 of 0.1512 μM.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Virus Protease | HIV Protease
Research Area

——
Indication

——

Chemical Information

CAS Number

2375781-06-7
Formula Weight

478.99
Molecular Formula

C23H25ClF2N4OS
Purity

>98% (HPLC)
Solubility

——
SMILES

ClC1=C(NN=C1CSC=2NC(CC3CCCCC3)=C(CC)C(=O)N2)C4=CC(F)=C(F)C=C4
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Rui RM, et al. C6-structural optimizations of 2-aryl-1H-pyrazole-S-DABOs: From anti-HIV to anti-DENV activity. Bioorg Chem. 2022 Feb;119:105494.?

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