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DENV-IN-5

CAS No. 2375781-06-7

DENV-IN-5( —— )

Catalog No. M35702 CAS No. 2375781-06-7

Denv-in-5 is an effective and selective dengue virus (DENV) inhibitor with EC50 values of 1.47, 9.23, 7.08, 8.91 μM for denV-I-IV and 0.1512 μM for HIV-1IIIB.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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10MG 1359 In Stock
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Biological Information

  • Product Name
    DENV-IN-5
  • Note
    Research use only, not for human use.
  • Brief Description
    Denv-in-5 is an effective and selective dengue virus (DENV) inhibitor with EC50 values of 1.47, 9.23, 7.08, 8.91 μM for denV-I-IV and 0.1512 μM for HIV-1IIIB.
  • Description
    DENV-IN-5 (Compound 4b) is a dengue virus (DENV) inhibitor with EC50s of 1.47, 9.23, 7.08 and 8.91 μM against DENV-I ～ IV replication, respectively. DENV-IN-5 also inhibits HIV-1IIIB strain with an EC50 of 0.1512 μM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Virus Protease | HIV Protease
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    2375781-06-7
  • Formula Weight
    478.99
  • Molecular Formula
    C23H25ClF2N4OS
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ClC1=C(NN=C1CSC=2NC(CC3CCCCC3)=C(CC)C(=O)N2)C4=CC(F)=C(F)C=C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Rui RM, et al. C6-structural optimizations of 2-aryl-1H-pyrazole-S-DABOs: From anti-HIV to anti-DENV activity. Bioorg Chem. 2022 Feb;119:105494.?
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