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HOIPIN-8 sodium
CAS No. 2519537-70-1
HOIPIN-8 sodium( —— )
Catalog No. M35672 CAS No. 2519537-70-1
HOIPIN-8 is a potent inhibitor of the linear ubiquitin chain assembly complex (LUBAC) with an IC50 of 11 nM. As a derivative of HOIPIN-1, it exhibits 255-fold greater inhibition of both petit-LUBAC and TNF-α-mediated NF-κB activation compared to HOIPIN-1.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 149 | In Stock |
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| 5MG | 148 | In Stock |
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| 10MG | 236 | In Stock |
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| 25MG | 377 | In Stock |
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| 50MG | 529 | In Stock |
|
| 100MG | 731 | In Stock |
|
| 200MG | 1004 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameHOIPIN-8 sodium
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NoteResearch use only, not for human use.
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Brief DescriptionHOIPIN-8 is a potent inhibitor of the linear ubiquitin chain assembly complex (LUBAC) with an IC50 of 11 nM. As a derivative of HOIPIN-1, it exhibits 255-fold greater inhibition of both petit-LUBAC and TNF-α-mediated NF-κB activation compared to HOIPIN-1.
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DescriptionHOIPIN-8 is a potent inhibitor of the linear ubiquitin chain assembly complex (LUBAC) with an IC50 of 11 nM. As a derivative of HOIPIN-1, it exhibits 255-fold greater inhibition of both petit-LUBAC and TNF-α-mediated NF-κB activation compared to HOIPIN-1. HOIPIN-8 is a promising tool to explore cellular functions of LUBAC.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayImmunology/Inflammation
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TargetIκB kinase (IKK)
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RecptorIκB/IKK
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Research Area——
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Indication——
Chemical Information
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CAS Number2519537-70-1
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Formula Weight456.38
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Molecular FormulaC23H15F2N4NaO3
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Purity>98% (HPLC)
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Solubility——
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SMILESO=C(C1=CC=C(C2=CN(C)N=C2)C=C1/C=C/C(C3=C(C=C(C4=CNN=C4)C=C3F)F)=O)[O-].[Na+]
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
molnova catalog
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