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WIN 54954
CAS No. 107355-45-3
WIN 54954( —— )
Catalog No. M35578 CAS No. 107355-45-3
WIN 54954 is an orally available antiviral agent that inhibits Coxsackievirus and inhibits viral translation or transcription.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 116 | In Stock |
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| 5MG | 103 | In Stock |
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| 10MG | 168 | In Stock |
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| 25MG | 306 | In Stock |
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| 50MG | 481 | In Stock |
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| 100MG | 770 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameWIN 54954
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NoteResearch use only, not for human use.
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Brief DescriptionWIN 54954 is an orally available antiviral agent that inhibits Coxsackievirus and inhibits viral translation or transcription.
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DescriptionWIN 54954 is an orally active and broad-spectrum antipicornavirus agent. WIN 54954 is effectiveness against human rhinovirus, echovirus 9 and enterovirus infections.
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In VitroWIN 54954 reduces plaque formation of 50 of 52 rhinovirus serotypes (MICs ranges from 0.007 to 2.2 μg/mL).WIN 54954 inhibits 15 commonly isolated enteroviruses, with an EC80 of 0.06 μg/mL.
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In VivoWIN 54954 (2-100 mg/kg; p.o.) protects 50% of the mice from developing paralysis following infection with coxsackievirus A-9 and echovirus-9 at the dose of 2 and 100 mg/kg, respectively.
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Synonyms——
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PathwayImmunology/Inflammation
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TargetAntiviral
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RecptorAntiviral
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Research Area——
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Indication——
Chemical Information
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CAS Number107355-45-3
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Formula Weight383.27
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Molecular FormulaC18H20Cl2N2O3
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (260.91 mM; Ultrasonic )
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SMILESCc1cc(CCCCCOc2c(Cl)cc(cc2Cl)C2=NCCO2)on1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Woods MG, et, al. In vitro and in vivo activities of WIN 54954, a new broad-spectrum antipicornavirus drug. Antimicrob Agents Chemother. 1989 Dec;33(12):2069-74.?
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