Diaziquone

Research use only, not for human use.

Diaziquone (NSC-182986) is a water-soluble synthetic azacyclic benzoquinone that enhances penetration of the blood-brain barrier, has antitumor activity, and is used in the treatment of extreme renal failure.

Diaziquone (Diaziquone) is a water-soluble, synthetic aziridinylbenzoquinone with potential antineoplastic activity.

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Diaziquone (6.75mg /sq m daily for 5 consecutive days or single-dose 26 mg/sq m) has a broad range of activity of diaziquone against primary nervous system tumors and has enhancement effect combined with either 1,3-bis(2-chloroethyl)-1-nitrosourea or procarbazine in athymic mice.Animal Model:Homozygous nu/nu BALB/c athymic mice Dosage:6.75mg /sq m or 26 mg/sq m Administration:6.75mg /sq m daily for 5 consecutive days or single-dose 26 mg/sq m Result:Showed rapid clearance in the plasma of athymic mice with a half-life of approximately 11.5 min.Produced significant growth delays.Produced significant increases in the median growth delay, significant increases in the number of tumor regressions.

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Others

Other Targets

Others

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57998-68-2

364.35

C16H20N4O6

>98% (HPLC)

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N(C(OCC)=O)C1=C(C(=O)C(NC(OCC)=O)=C(C1=O)N2CC2)N3CC3

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(-20℃)

With Ice Pack

≥ 2 years