Wnt/β-catenin agonist 4
CAS No. 912784-79-3
Wnt/β-catenin agonist 4( —— )
Catalog No. M35475 CAS No. 912784-79-3
Wnt/β-catenin agonist 4 is an agonist of Wnt that activates Wnt/β-catenin signaling and directs signaling.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 61 | Get Quote |
|
| 10MG | 100 | Get Quote |
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| 25MG | 177 | Get Quote |
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| 50MG | 302 | Get Quote |
|
| 100MG | 484 | Get Quote |
|
| 500MG | 1035 | Get Quote |
|
| 1G | Get Quote | Get Quote |
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Biological Information
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Product NameWnt/β-catenin agonist 4
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NoteResearch use only, not for human use.
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Brief DescriptionWnt/β-catenin agonist 4 is an agonist of Wnt that activates Wnt/β-catenin signaling and directs signaling.
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DescriptionWnt/β-catenin agonist 4 (Derivative 83) is an agonist of Wnt that activates Wnt/β-catenin signal transmission.
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In VitroWnt/β-catenin agonist 4 (Derivative 83) (120 μM; 24 h) shows 1049% β-catenin activity in HEK293 and SW480 cells.Wnt/β-catenin agonist 4 (11 μM; 4 days) shows 2848% ALP activity on differentiation of ST2 cell line into osteoblasts.
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In Vivo——
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Synonyms——
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PathwayWnt/Notch/Hedgehog
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TargetWnt/beta/catenin
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RecptorWnt/beta-catenin
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Research Area——
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Indication——
Chemical Information
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CAS Number912784-79-3
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Formula Weight314.31
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Molecular FormulaC16H15FN4O2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 125 mg/mL (397.70 mM; Ultrasonic )
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SMILESFc1ccc(cc1)-c1cc(no1)C(=O)NCCCn1ccnc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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TNIK-IN-3
TNIK-IN-3 is a highly potent and orally active inhibitor of Traf2- and Nck-interacting protein kinase (TNIK). It exhibits a strong selectivity for TNIK with an IC50 value of 0.026 μM.
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MSAB
MSAB is a selective inhibitor of Wnt/β-catenin signaling.?MSAB binds to β-catenin, promoting its degradation, and specifically downregulates Wnt/β-catenin target genes.MSAB act against Wnt/β-catenin signaling and identified ?as a selective inhibitor of Wnt/β-catenin signaling.?
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β-Elemonic Acid
Beta-Elemonic acid inhibits proliferation by inducing hypoploid cells and cell apoptosis, the anticancer effects of beta-Elemonic acid are related to the MAPK signaling pathway, ROS activation and glutathione depletion in human A549 lung cancer cells.
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