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SARS-CoV-2-IN-14
CAS No. 22203-98-1
SARS-CoV-2-IN-14( —— )
Catalog No. M35435 CAS No. 22203-98-1
SARS-CoV-2-IN-14 is a potent and oral inhibitor of SARS-CoV-2 (IC50:0.39 μM), which is an analogue of niclosamide.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 29 | In Stock |
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| 10MG | 36 | In Stock |
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| 25MG | 56 | In Stock |
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| 50MG | 86 | In Stock |
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| 100MG | 127 | In Stock |
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| 200MG | 184 | In Stock |
|
| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product NameSARS-CoV-2-IN-14
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NoteResearch use only, not for human use.
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Brief DescriptionSARS-CoV-2-IN-14 is a potent and oral inhibitor of SARS-CoV-2 (IC50:0.39 μM), which is an analogue of niclosamide.
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DescriptionSARS-CoV-2-IN-14 (compound 6) is a potent inhibitor of SARS-CoV-2 with an IC50 of 0.39 μM. SARS-CoV-2-IN-14 is a niclosamide analogue. SARS-CoV-2-IN-14 contains higher stability in human plasma and liver S9 enzymes assay than niclosamide, which can improve bioavailability and half-life when administered orally.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorSARS-CoV
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Research Area——
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Indication——
Chemical Information
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CAS Number22203-98-1
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Formula Weight282.12
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Molecular FormulaC13H9Cl2NO2
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 250 mg/mL (886.15 mM; Ultrasonic )
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SMILESC(NC1=CC(Cl)=CC=C1)(=O)C2=C(O)C=CC(Cl)=C2
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Juang YP, et al. Design, synthesis and biological evaluations of niclosamide analogues against SARS-CoV-2. Eur J Med Chem. 2022 May 5;235:114295.?
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