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M3541

CAS No. 1360628-91-6

M3541( —— )

Catalog No. M36357 CAS No. 1360628-91-6

M3541 is a selectively potent and orally active ATM inhibitor with potential antitumor activity.M-3541 inhibits ATM kinase activity and ATM-mediated signaling by binding to ATM.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

M3541
Note

Research use only, not for human use.
Brief Description

M3541 is a selectively potent and orally active ATM inhibitor with potential antitumor activity.M-3541 inhibits ATM kinase activity and ATM-mediated signaling by binding to ATM.
Description

DNA-PK-IN-11 is a DNA-PK inhibitor with an IC50 of <0.1 μM (DE102010035744A1; compound 36).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Apoptosis
Target

Apoptosis
Recptor

Apoptosis | ATM/ATR
Research Area

——
Indication

——

Chemical Information

CAS Number

1360628-91-6
Formula Weight

428.42
Molecular Formula

C23H17FN6O2
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 5 mg/mL (11.67 mM; Ultrasonic (<60°C)
SMILES

O=C1N(C=2C=3C(=CC(OC)=C(C3)C4=CN(C)N=C4)N=CC2N1C)C5=C(F)C=C(C#N)C=C5
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Dr. Fuchss Thomas, et al. Imidazolonylchinoline. DE102010035744A1.

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