Lurtotecan
CAS No. 149882-10-0
Lurtotecan( —— )
Catalog No. M35356 CAS No. 149882-10-0
Lurtotecan (GI147211) is a semisynthetic Camptothecin analog. Lurtotecan is a topoisomerase I inhibitor with anticancer effects.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 565 | In Stock |
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| 10MG | 847 | In Stock |
|
| 25MG | 1492 | In Stock |
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| 50MG | 2009 | In Stock |
|
| 100MG | 2716 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameLurtotecan
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NoteResearch use only, not for human use.
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Brief DescriptionLurtotecan (GI147211) is a semisynthetic Camptothecin analog. Lurtotecan is a topoisomerase I inhibitor with anticancer effects.
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DescriptionLurtotecan (GI147211; OSI-211), a semisynthetic Camptothecin analog, is a topoisomerase I inhibitor. Lurtotecan has anticancer effects.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayCell Cycle/DNA Damage
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TargetTopoisomerase
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RecptorTopoisomerase
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Research Area——
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Indication——
Chemical Information
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CAS Number149882-10-0
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Formula Weight518.56
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Molecular FormulaC28H30N4O6
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 4.33 mg/mL (8.35 mM; Ultrasonic )
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SMILESCC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4cc5OCCOc5cc4c(CN4CCN(C)CC4)c3Cn1c2=O
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
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SW-044248
SW-044248 is a novel selective inhibitor of Topoisomerase I; inhibits Top I differently from camptothecin.
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Exatecan Mesylate
Exatecan Mesylate is a DNA topoisomerase I inhibitor (IC50: 2.2 μM, 0.975 μg/mL).Exatecan Mesylate (DX-8951f) significantly inhibits the proliferation of several cancer cell lines, with mean GI50s of 2.02 ng/mL, 2.92 ng/mL, 1.53 ng/mL, and 0.877 ng/mL for breast cancer cells, colon cancer cells, stomach cancer cells and lung cancer cells, respectively.
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Lucidin primeverosid...
Lucidin primeveroside is a natural product isolated from the root powder of akane (Rubia akane) and can be used as a coloring agent and a food pigment. Lucidin primeveroside can be metabolically converted to genotoxic compound Lucidin in mice.
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