MitoBloCK-6

CAS No. 303215-67-0

MitoBloCK-6( —— )

Catalog No. M35338 CAS No. 303215-67-0

MitoBloCK-6 is a potent Erv1/ALR inhibitor with IC50 values of 900 nM and 700 nM, respectively, and also inhibits Erv2 with an IC50 of 1.4 μM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 31 In Stock
10MG 45 In Stock
25MG 72 In Stock
50MG 117 In Stock
100MG 183 In Stock
200MG 276 In Stock
500MG 480 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    MitoBloCK-6
  • Note
    Research use only, not for human use.
  • Brief Description
    MitoBloCK-6 is a potent Erv1/ALR inhibitor with IC50 values of 900 nM and 700 nM, respectively, and also inhibits Erv2 with an IC50 of 1.4 μM.
  • Description
    MitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 (IC50=1.4 μM). MitoBloCK-6 can induce apoptosis via cytochrome c release in hESCs.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Apoptosis
  • Target
    Apoptosis
  • Recptor
    Apoptosis
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    303215-67-0
  • Formula Weight
    357.23
  • Molecular Formula
    C19H14Cl2N2O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (139.97 mM)
  • SMILES
    Oc1c(Cl)cc(Cl)cc1\C=N\c1ccc(Nc2ccccc2)cc1
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Dabir DV, et, al. A small molecule inhibitor of redox-regulated protein translocation into mitochondria. Dev Cell. 2013 Apr 15;25(1):81-92. ?
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