WAY-118959-A( —— )

Catalog No. M35317 CAS No. 315703-81-2

WAY-118959-A is a potential microtubule acetylation inhibitor.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	261	In Stock
5MG	255	In Stock
10MG	375	In Stock
25MG	562	In Stock
50MG	770	In Stock
100MG	1051	In Stock
200MG	1423	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

WAY-118959-A
Note

Research use only, not for human use.
Brief Description

WAY-118959-A is a potential microtubule acetylation inhibitor.
Description

GM-90257 is a microtubule acetylation inhibitor that binds directly to α-tubulin. GM-90257 prevents the recruitment of α-tubulin acetyltransferase 1 (αTAT1) to the K40 residue in α-tubulin. GM-90257 causes the apoptosis of MDA-MB-231 cells with weaker effects on MCF-10A or MCF-7 cells, which have a relatively low level of microtubule acetylation.
In Vitro

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In Vivo

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Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Microtubule Associated
Research Area

——
Indication

——

Chemical Information

CAS Number

315703-81-2
Formula Weight

342.44
Molecular Formula

C16H14N4OS2
Purity

>98% (HPLC)
Solubility

——
SMILES

COC1=CC=C(NC2=NC(=CS2)C2=C(C)N=C3SC=CN23)C=C1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Ahreum Kwon, et al. Potent Small-Molecule Inhibitors Targeting Acetylated Microtubules as Anticancer Agents Against Triple-Negative Breast Cancer. Biomedicines. 2020 Sep 9;8(9):338. ?

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