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Home - Products - Others - Other Targets - N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4-cyanobiphenyl-2-carboxaMide

N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4-cyanobiphenyl-2-carboxaMide

CAS No. 1383373-65-6

N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4-cyanobiphenyl-2-carboxaMide( —— )

Catalog No. M35310 CAS No. 1383373-65-6

N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nM.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 278 In Stock
5MG 255 In Stock
10MG 375 In Stock
25MG 562 In Stock
50MG 770 In Stock
100MG 1051 In Stock
200MG 1423 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock
Get Quotation Bulk Inquiry Add to Cart

Biological Information

  • Product Name
    N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4-cyanobiphenyl-2-carboxaMide
  • Note
    Research use only, not for human use.
  • Brief Description
    N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nM.
  • Description
    TAU-IN-1 (compound 051) is a TAU protein inhibitor with an EC50 value of 325 nM. TAU-IN-1 can be used in the study of neurodegenerative diseases.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Microtubule Associated
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1383373-65-6
  • Formula Weight
    399.87
  • Molecular Formula
    C24H18ClN3O
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(CNC(=O)C1=C(C=CC=C1)C2=CC=C(C#N)C=C2)C=3C=4C(NC3)=CC=C(Cl)C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Gerard Griffioen et al. Novel compounds for the treatment of neurodegenerative diseases. WO2012080220A1.2012-06-21.
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