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N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4-cyanobiphenyl-2-carboxaMide
N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4-cyanobiphenyl-2-carboxaMide
CAS No. 1383373-65-6
N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4-cyanobiphenyl-2-carboxaMide( —— )
Catalog No. M35310 CAS No. 1383373-65-6
N-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 278 | In Stock |
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| 5MG | 255 | In Stock |
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| 10MG | 375 | In Stock |
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| 25MG | 562 | In Stock |
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| 50MG | 770 | In Stock |
|
| 100MG | 1051 | In Stock |
|
| 200MG | 1423 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product NameN-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4-cyanobiphenyl-2-carboxaMide
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NoteResearch use only, not for human use.
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Brief DescriptionN-[2-(5-Chloro-1H-indol-3-yl)ethyl]-4'-cyanobiphenyl-2-carboxaMide, a TAU cytotoxicity inhibitor, inhibits LDH leakage of M17-TAU P301L cells with EC50 of 325nM.
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DescriptionTAU-IN-1 (compound 051) is a TAU protein inhibitor with an EC50 value of 325 nM. TAU-IN-1 can be used in the study of neurodegenerative diseases.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorMicrotubule Associated
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Research Area——
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Indication——
Chemical Information
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CAS Number1383373-65-6
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Formula Weight399.87
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Molecular FormulaC24H18ClN3O
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Purity>98% (HPLC)
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Solubility——
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SMILESC(CNC(=O)C1=C(C=CC=C1)C2=CC=C(C#N)C=C2)C=3C=4C(NC3)=CC=C(Cl)C4
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Gerard Griffioen et al. Novel compounds for the treatment of neurodegenerative diseases. WO2012080220A1.2012-06-21.
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