cis-Vaccenic acid

Research use only, not for human use.

cis-Vaccenic acid (Asclepic acid) is the antiviral extract from Rhodopseudomonas capsulate and the predominant active component of Rhodopseudomonas capsulate. cis-Vaccenic acid acts a potential fetal hemoglobin inducer.

cis-Vaccenic acid, the antiviral extract from Rhodopseudomonas capsulate and the predominant active component of Rhodopseudomonas capsulate, acts a potential fetal hemoglobin inducer.

cis-Vaccenic acid (CVA) (50 μM, 70 μM and 100 μM) induces differentiation and up-regulates gamma globin synthesis in K562, JK1 and transgenic mice erythroid progenitor stem cells. cis-Vaccenic acid (50 μM) also increased the percentage of benzidine positive JK-1 cell.Cell Differentiation Assay Cell Line:K562 cells Concentration:50 μM, 70 μM and 100 μM Incubation Time:48 and 120 hours Result:Induced differentiation appeared to be concentration dependent in K562 cells with 50 μM CVA being the most effective concentration with more than 20% of the K562 cells showing positive for Benzidine stain after 48 h of incubation with CVA.

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Immunology/Inflammation

Antiviral

Antiviral

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506-17-2

282.46

C18H34O2

>98% (HPLC)

In Vitro:?DMSO : ≥ 50 mg/mL (177.02 mM )

C(CCC/C=C\CCCCCC)CCCCCC(O)=O

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(-20℃)

With Ice Pack

≥ 2 years