NH2-PEG2-C6-Cl hydrochloride( —— )

Catalog No. M35234 CAS No. 1035373-85-3

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Datasheet

HNMR

HPLC

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Product Name

NH2-PEG2-C6-Cl hydrochloride
Note

Research use only, not for human use.
Brief Description

NH2-PEG2-C6-Cl hydrochloride is a PROTAC linker belonging to the PEG class and can be used to synthesize PROTAC molecules.
Description

2-(2-(6-chlorohexyloxy)ethoxy)ethanamine (hydrochloride) is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
In Vitro

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
In Vivo

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Synonyms

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Pathway

Others
Target

Other Targets
Recptor

PROTACs
Research Area

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Indication

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1. Nalawansha DA, et al. PROTACs: An Emerging Therapeutic Modality in Precision Medicine. Cell Chem Biol. 2020;27(8):998-985.?

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