FATP1-IN-2( —— )

Catalog No. M35196 CAS No. 2650944-83-3

FATP1-IN-2 is a fatty acid transporter protein 1 (FATP1) inhibitor with oral activity for the study of obesity and metabolic diseases.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

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Biological Information

Product Name

FATP1-IN-2
Note

Research use only, not for human use.
Brief Description

FATP1-IN-2 is a fatty acid transporter protein 1 (FATP1) inhibitor with oral activity for the study of obesity and metabolic diseases.
Description

FATP1-IN-2 (compound 12a), an arylpiperazine derivative, is an orally active fatty acid transport protein 1 (FATP1) inhibitor (human IC50=0.43 μM, mouse IC50=0.39 μM).
In Vitro

——
In Vivo

Animal Model:Mice Dosage:10 mg/kg Administration:P.o.Result:Showed a Cmax value above the mouse IC50 value.
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

Others
Research Area

——
Indication

——

Chemical Information

CAS Number

2650944-83-3
Formula Weight

353.39
Molecular Formula

C19H20FN5O
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 100 mg/mL (282.97 mM; Ultrasonic )
SMILES

Cc1nc2ccccn2c1C(=O)CN1CCN(CC1)c1ccc(F)cn1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Matsufuji T, et al. Arylpiperazines as fatty acid transport protein 1 (FATP1) inhibitors with improved potency and pharmacokinetic properties. Bioorg Med Chem Lett. 2013;23(9):2560-2565.?

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