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(4-NH2)-Exatecan
CAS No. 2495742-21-5
(4-NH2)-Exatecan( —— )
Catalog No. M35185 CAS No. 2495742-21-5
(4-NH2)-Exatecan is a topoisomerase inhibitor with potential anticancer activity for the synthesis of antibody drug conjugates (ADCs).
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 282 | In Stock |
|
| 10MG | 471 | In Stock |
|
| 25MG | 708 | In Stock |
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| 50MG | 918 | In Stock |
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| 100MG | 1349 | In Stock |
|
| 200MG | Get Quote | In Stock |
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| 500MG | Get Quote | In Stock |
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| 1G | Get Quote | In Stock |
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Biological Information
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Product Name(4-NH2)-Exatecan
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NoteResearch use only, not for human use.
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Brief Description(4-NH2)-Exatecan is a topoisomerase inhibitor with potential anticancer activity for the synthesis of antibody drug conjugates (ADCs).
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Description(4-NH2)-Exatecan, a topoisomerase inhibitor, is a derivative of Exatecan. (4-NH2)-Exatecan can be used in the synthesis of antibody-drug conjugates (ADCs) (US20200306243A1, compound A).
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayAntibody Drug Conjugates (ADC)
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TargetADC Cytotoxin
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RecptorADC Cytotoxin | Topoisomerase
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Research Area——
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Indication——
Chemical Information
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CAS Number2495742-21-5
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Formula Weight403.43
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Molecular FormulaC23H21N3O4
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 100 mg/mL (247.87 mM; Ultrasonic )
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SMILESCC[C@@]1(O)C(=O)OCc2c1cc1-c3nc4ccc(N)c5CCCc(c3Cn1c2=O)c45
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Howard PW, et, al. Compounds and conjugates thereof. US20200306243A1.
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