Cart
sales@molnova.com
NF-κΒ activator 1
CAS No. 2387524-59-4
NF-κΒ activator 1( —— )
Catalog No. M35172 CAS No. 2387524-59-4
NF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 223 | In Stock |
|
| 5MG | 202 | In Stock |
|
| 10MG | 330 | In Stock |
|
| 25MG | 560 | In Stock |
|
| 50MG | 783 | In Stock |
|
| 100MG | 1079 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | 2167 | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameNF-κΒ activator 1
-
NoteResearch use only, not for human use.
-
Brief DescriptionNF-κΒ activator 1 can activate the nf-kappa Β gene activator, EC50 of 0.9 microns.
-
DescriptionNF-κΒ activator 1 is a potent NF-κΒ activator with an EC50 of 0.9 μM. NF-κΒ activator 1 induces superoxide dismutase (SOD)2 mRNA expression.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetNF-κB
-
RecptorNF-κB
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2387524-59-4
-
Formula Weight314.33
-
Molecular FormulaC16H11FN2O2S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (318.14 mM; Ultrasonic )
-
SMILESOC(=O)c1cccc(c1)-c1csc(Nc2ccccc2F)n1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Mathew B, et al. Structure-activity relationship (SAR) studies of N-(3-methylpyridin-2-yl)-4-(pyridin-2-yl)thiazol-2-amine (SRI-22819) as NF-?B activators for the treatment of ALS [published online ahead of print, 2020 Oct 22]. Eur J Med Chem. 2020;112952.?
molnova catalog
related products
-
Scopolin
Scopolin can reduce the clinical symptoms of rat AIA by inhibiting inflammation and angiogenesis, and this compound may be a potent agent for angiogenesis related diseases and can serve as a structural base for screening more potent synthetic analogs.
-
BAY 11-7085
An inhibitor of the expression of ICAM-1, VCAM-1, and E-selectin in human endothelial cells (IC50=5-10 uM).
-
IT-603
A small molecule inhibitor of the NF-κB family member c-Rel with IC50 of 3 uM in EMSA assays.
