KSC-34

Research use only, not for human use.

KSC-34 is a covalent modifier of protein disulfide isomerase A1 (PDIA1).KSC-34 is a selective inhibitor targeting the a-site of PDIA1.

KSC-34, a covalent modifier of protein disulfide isomerase A1 (PDIA1), is also a selective and potent a-site inhibitor of PDIA1 with an IC50 of 3.5 μM. KSC-34 displays a 30-fold selectivity for a domain over a′ domain and displays high selectivity for PDIA1 in complex proteomes with minimal engagement of other members of the PDI family. KSC-34 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.

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Others

Other Targets

Others

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2226201-97-2

429.95

C21H28ClN7O

>98% (HPLC)

In Vitro:?DMSO : 100 mg/mL (232.59 mM; Ultrasonic )

O=C(NCCNC1=NC(=NC(=N1)N(C)CCCCC=2C=CC=CC2)NCC#C)CCl

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(-20℃)

With Ice Pack

≥ 2 years