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tri-GalNAc-COOH

CAS No. 1953146-81-0

tri-GalNAc-COOH( —— )

Catalog No. M35114 CAS No. 1953146-81-0

Tri-GalNAc-COOH is a ligand for the asialoglycoprotein receptor (ASGPR) and is commonly used in lysosomal targeting chimera (LYTAC) investigations.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
1 mL x 10 mM in DMSO 1159 In Stock
5MG 607 In Stock
10MG 846 In Stock
25MG 1302 In Stock
50MG 1702 In Stock
100MG 2316 In Stock
200MG Get Quote In Stock
500MG 4631 In Stock
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Biological Information

  • Product Name
    tri-GalNAc-COOH
  • Note
    Research use only, not for human use.
  • Brief Description
    Tri-GalNAc-COOH is a ligand for the asialoglycoprotein receptor (ASGPR) and is commonly used in lysosomal targeting chimera (LYTAC) investigations.
  • Description
    tri-GalNAc-COOH is an asialoglycoprotein receptor (ASGPR) ligand that can be used for LYsosome TArgeting Chimera (LYTAC) research.
  • In Vitro
    tri-GalNAc-COOH is a biotin-free ASGPR ligand, which failes to deliver NA-650 to HepG2, Huh7, or A549 cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    LYTACs
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1953146-81-0
  • Formula Weight
    1735.91
  • Molecular Formula
    C75H134N10O35
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (144.02 mM; Ultrasonic )
  • SMILES
    CC(=O)N[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1OCCCCC(=O)NCCCNC(=O)CCOCC(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1NC(C)=O)(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1NC(C)=O)NC(=O)CCOCCOCCOCCOCCOCCC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Yaxian Zhou, et al. Development of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins. ACS Cent Sci. 2021 Mar 24;7(3):499-506.?
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