tri-GalNAc-COOH

CAS No. 1953146-81-0

tri-GalNAc-COOH( —— )

Catalog No. M35114 CAS No. 1953146-81-0

Tri-GalNAc-COOH is a ligand for the asialoglycoprotein receptor (ASGPR) and is commonly used in lysosomal targeting chimera (LYTAC) investigations.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 388 Get Quote
5MG 607 Get Quote
10MG 846 Get Quote
25MG 1260 Get Quote
50MG 1684 Get Quote
100MG 2241 Get Quote
500MG 4482 Get Quote
1G Get Quote Get Quote

Biological Information

  • Product Name
    tri-GalNAc-COOH
  • Note
    Research use only, not for human use.
  • Brief Description
    Tri-GalNAc-COOH is a ligand for the asialoglycoprotein receptor (ASGPR) and is commonly used in lysosomal targeting chimera (LYTAC) investigations.
  • Description
    tri-GalNAc-COOH is an asialoglycoprotein receptor (ASGPR) ligand that can be used for LYsosome TArgeting Chimera (LYTAC) research.
  • In Vitro
    tri-GalNAc-COOH is a biotin-free ASGPR ligand, which failes to deliver NA-650 to HepG2, Huh7, or A549 cells.
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    LYTACs
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1953146-81-0
  • Formula Weight
    1735.91
  • Molecular Formula
    C75H134N10O35
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 250 mg/mL (144.02 mM; Ultrasonic )
  • SMILES
    CC(=O)N[C@@H]1[C@@H](O)[C@@H](O)[C@@H](CO)O[C@H]1OCCCCC(=O)NCCCNC(=O)CCOCC(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1NC(C)=O)(COCCC(=O)NCCCNC(=O)CCCCO[C@@H]1O[C@H](CO)[C@H](O)[C@H](O)[C@H]1NC(C)=O)NC(=O)CCOCCOCCOCCOCCOCCC(O)=O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Yaxian Zhou, et al. Development of Triantennary N-Acetylgalactosamine Conjugates as Degraders for Extracellular Proteins. ACS Cent Sci. 2021 Mar 24;7(3):499-506.?
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