Cart
sales@molnova.com
3-Hydroxykynurenine
CAS No. 484-78-6
3-Hydroxykynurenine( —— )
Catalog No. M34973 CAS No. 484-78-6
3-Hydroxykynurenine (3-hydroxy-DL-Kynurenine) is an active metabolite of tryptophan and inhibits yeast and rat liver aldehyde dehydrogenase by 97 and 69%.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 29 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name3-Hydroxykynurenine
-
NoteResearch use only, not for human use.
-
Brief Description3-Hydroxykynurenine (3-hydroxy-DL-Kynurenine) is an active metabolite of tryptophan and inhibits yeast and rat liver aldehyde dehydrogenase by 97 and 69%.
-
Description3-Hydroxykynurenine, a metabolite of tryptophan, is a potential endogenous neurotoxin whose increased levels have been described in several neurodegenerative disorders. 3-Hydroxykynurenine induces neuronal apoptosis.
-
In VitroCell Proliferation Assay Cell Line:CD3/CD28 bead-stimulated CD4+?T cells Concentration:0, 20, 40, 60, 80, and 100 μM Incubation Time:72 hours Result:Significantly inhibited CD4+?T-cell proliferation in a dose-dependent manner with an IC50?of approximately 70 μM.
-
In Vivo——
-
Synonyms——
-
PathwayOthers
-
TargetOther Targets
-
RecptorOthers
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number484-78-6
-
Formula Weight224.21
-
Molecular FormulaC10H12N2O4
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?1M HCl : 33.33 mg/mL (148.66 mM; Ultrasonic; (HCL ，pH≈1))
-
SMILESNC(CC(=O)c1cccc(O)c1N)C(O)=O
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. S Okuda,?et al. 3-Hydroxykynurenine, an endogenous oxidative stress generator, causes neuronal cell death with apoptotic features and region selectivity. J Neurochem.?1998 Jan;70(1):299-307.?
molnova catalog
related products
-
[Des-Thr7]-Glucagon
(Des-Thr7)-Glucagon is a polypeptide that can be found by peptide screening. Peptide screening is a research tool that pools active peptides primarily by immunoassay. Peptide screening can be used for protein interaction, functional analysis, epitope screening, especially in the field of agent research and development.
-
TSHR antagonist S37
TSHR antagonist S37 is a selective and competitive antagonist of the thyrotropin receptor (TSHR).
-
(S)-(-)-1-Phenyletha...
1-Phenylethanol exists as a solid soluble (in water) and a very weakly acidic compound (based on its pKa).
