Cart
sales@molnova.com
VEGFR-2-IN-6
CAS No. 444731-47-9
VEGFR-2-IN-6( —— )
Catalog No. M34911 CAS No. 444731-47-9
VEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis .
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 250 | In Stock |
|
| 5MG | 227 | In Stock |
|
| 10MG | 353 | In Stock |
|
| 100MG | Get Quote | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameVEGFR-2-IN-6
-
NoteResearch use only, not for human use.
-
Brief DescriptionVEGFR-2-IN-6 (WO 02/059110, example 64) is a potent inhibitor of VEGFR2, a crucial receptor involved in the regulation of angiogenesis .
-
DescriptionVEGFR-2-IN-6 (example 64) is a VEGFR2 inhibitor (angiogenesis modulator), which is extracted from patent WO 02/059110.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayAngiogenesis
-
TargetVEGFR
-
RecptorVEGFR
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number444731-47-9
-
Formula Weight423.49
-
Molecular FormulaC20H21N7O2S
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 25 mg/mL (59.03 mM; Ultrasonic )
-
SMILESCN(c1ccc2c(C)n[nH]c2c1)c1ccnc(Nc2ccc(C)c(c2)S(N)(=O)=O)n1
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Glaxo Wellcome House, et al. PYRIMIDINEAMINES AS ANGIOGENESIS MODULATORS. Patent WO 02/059110.
molnova catalog
related products
-
PAN-90806
PAN-90806 (CP-547632, CP547632) is a highly potent, ATP-competitive, orally active VEGFR-2 inhibitor that blocks VEGFR-2 kinase autophosphorylation (IC50=11 nM) and VEGF-induced VEGFR-2 phosphorylation (IC50=5 nM).
-
Apatinib Mesylate
Apatinib (YN968D1) is a multitargeted tyrosine kinase inhibitor (TKI) that inhibits VEGFR-2 (Flk-1/KDR, IC50=1 nM), RET, c-Kit and c-Src (IC50=13, 429 and 530 nM respectively).
-
(Z)-FeCP-oxindole
(Z)-FeCP-oxindole is a selective inhibitor of VEGFR2 with an IC50 of 200 nM for humans and demonstrates anticancer activity.
