ML 315

CAS No. 1440251-53-5

ML 315( —— )

Catalog No. M34876 CAS No. 1440251-53-5

ML 315 is a selective Clk and DYRK inhibitor with potential anticancer activity for the study of neurological disorders.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 93 In Stock
10MG 155 In Stock
25MG 330 In Stock
50MG 529 In Stock
100MG 756 In Stock
200MG Get Quote In Stock
500MG 1516 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    ML 315
  • Note
    Research use only, not for human use.
  • Brief Description
    ML 315 is a selective Clk and DYRK inhibitor with potential anticancer activity for the study of neurological disorders.
  • Description
    ML 315 is a selective dual inhibitor of CDK and DYRK with IC50s of 68 nM and 282 nM, respectively. ML 315 is used in cancer and neurological disease research.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    DYRK | CDK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1440251-53-5
  • Formula Weight
    374.22
  • Molecular Formula
    C18H13Cl2N3O2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    ClC=1C=C(Cl)C=C(C1)CNC=2N=CN=CC2C3=CC=C4OCOC4=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Coombs TC, et al. Small-molecule pyrimidine inhibitors of the cdc2-like (Clk) and dual specificity tyrosine phosphorylation-regulated (Dyrk) kinases: development of chemical probe ML315. Bioorg Med Chem Lett. 2013 Jun 15;23(12):3654-61.?
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