p38 MAPK Inhibitor

CAS No. 219138-24-6

p38 MAPK Inhibitor( —— )

Catalog No. M34809 CAS No. 219138-24-6

p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogene RAS.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 294 In Stock
10MG 459 In Stock
25MG 677 In Stock
50MG 910 In Stock
100MG 1209 In Stock
200MG 1646 In Stock
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Biological Information

  • Product Name
    p38 MAPK Inhibitor
  • Note
    Research use only, not for human use.
  • Brief Description
    p38 MAPK inhibitor is a potent inhibitor of p38 MAP kinase (IC50 = 35 nM). It inhibits senescence induced by the oncogene RAS.
  • Description
    p38 MAPK-IN-4 (compound 6) is a p38 MAPK inhibitor with an 50 of 35 nM.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    MAPK/ERK Signaling
  • Target
    p38 MAPK
  • Recptor
    p38 MAPK
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    219138-24-6
  • Formula Weight
    365.79
  • Molecular Formula
    C20H13ClFN3O
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 20 mg/mL (54.68 mM; ultrasonic and adjust pH to 2 with 1M HCl)
  • SMILES
    O=C1C(=C(NN1C2=CC=C(Cl)C=C2)C=3C=CN=CC3)C4=CC=C(F)C=C4
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. S E de Laszlo, et al. Pyrroles and other heterocycles as inhibitors of p38 kinase. Bioorg Med Chem Lett. 1998 Oct 6;8(19):2689-94.?
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