Cart
sales@molnova.com
Dynapyrazole A
CAS No. 2226517-75-3
Dynapyrazole A( —— )
Catalog No. M34768 CAS No. 2226517-75-3
Dynapyrazole A is a specific inhibitor of microtubule dynamin with IC50s of 2.3 and 2.6 μM for dynein 1 and dynein 2-dependent microtubule gliding, and it inhibits Hedgehog signaling with an IC50 of 1.9 μM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 5MG | 41 | Get Quote |
|
| 10MG | 69 | Get Quote |
|
| 25MG | 143 | Get Quote |
|
| 50MG | 244 | Get Quote |
|
| 100MG | 354 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameDynapyrazole A
-
NoteResearch use only, not for human use.
-
Brief DescriptionDynapyrazole A is a specific inhibitor of microtubule dynamin with IC50s of 2.3 and 2.6 μM for dynein 1 and dynein 2-dependent microtubule gliding, and it inhibits Hedgehog signaling with an IC50 of 1.9 μM.
-
DescriptionDynapyrazole A is a specific inhibitor of microtubule dynamin that specifically inhibits the ATPase activity of microtubule-stimulated dynamin without blocking microtubule-independent basal activity.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayCytoskeleton/Cell Adhesion Molecules
-
TargetDynamin
-
RecptorDynamin
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number2226517-75-3
-
Formula Weight486.69
-
Molecular FormulaC20H12ClIN4O
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 25 mg/mL (51.37 mM; Ultrasonic (<60°C)
-
SMILESClc1ccc(cc1)C1(CC1)c1nn2c([nH]c(=O)c3cc(I)ccc23)c1C#N
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Zhaoyang Jing, et al. Rotavirus Viroplasm Biogenesis Involves Microtubule-Based Dynein Transport Mediated by an Interaction between NSP2 and Dynein Intermediate Chain. J Virol. 2021 Oct 13;95(21):e0124621.??
molnova catalog
related products
-
DRP1 inhibitor 4
DRP1 inhibitor 4 is a selective, small molecule inhibitor of the mammalian mitochondrial division dynamin, DRP1 with IC50 of 1.0 uM.
-
Dynamin IN-2
Dynamin IN-2 (compound 43) is a Wiskostatin analogue. Dynamin IN-2 is a potent dynamin inhibitor (dynamin I GTPase, IC50= 1.0 μM). Dynamin IN-2 blocks clathrin mediated endocytosis (CME) (IC50= 9.5 μM).
-
Mdivi 1
Mdivi-1 is a selective cell-permeable inhibitor of mitochondrial division DRP1 (dynamin-related GTPase) and mitochondrial division Dynamin I (Dnm1) with IC50 of 1-10 μM.
