LM-1685

CAS No. 416901-58-1

LM-1685( —— )

Catalog No. M34643 CAS No. 416901-58-1

LM-1685 is a potent and selective inhibitor of COX-2 IN human monocytes and whole blood with IC50 of 0.65μM and IC50 = 4.3μM, respectively, and is a potential compound for the treatment of inflammation.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 331 In Stock
10MG 451 In Stock
25MG 634 In Stock
50MG 768 In Stock
100MG 977 In Stock
200MG 1274 In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    LM-1685
  • Note
    Research use only, not for human use.
  • Brief Description
    LM-1685 is a potent and selective inhibitor of COX-2 IN human monocytes and whole blood with IC50 of 0.65μM and IC50 = 4.3μM, respectively, and is a potential compound for the treatment of inflammation.
  • Description
    COX-2-IN-5 (compound 11a) is a potent COX-2 inhibitor with an IC50 value of 0.65 μM. COX-2-IN-5 has the potential for the research of inflammation.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Chromatin/Epigenetic
  • Target
    COX
  • Recptor
    COX
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    416901-58-1
  • Formula Weight
    377.84
  • Molecular Formula
    C18H16ClNO4S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(N1C=2C(C=C1C(OC)=O)=CC(S(C)(=O)=O)=CC2)C3=CC=C(Cl)C=C3
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Palomer A, et al. Identification of novel cyclooxygenase-2 selective inhibitors using pharmacophore models. J Med Chem. 2002 Mar 28;45(7):1402-11.?
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