Cart
sales@molnova.com
Cipepofol
CAS No. 1637741-58-2
Cipepofol( —— )
Catalog No. M34620 CAS No. 1637741-58-2
Cipepofol (HSK3486) is a GABAA receptor agonist with sedative properties and protective effects in a variety of cardiovascular diseases.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 154 | In Stock |
|
| 5MG | 153 | In Stock |
|
| 10MG | 238 | In Stock |
|
| 25MG | 468 | In Stock |
|
| 50MG | 680 | In Stock |
|
| 100MG | 1079 | In Stock |
|
| 200MG | 1460 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product NameCipepofol
-
NoteResearch use only, not for human use.
-
Brief DescriptionCipepofol (HSK3486) is a GABAA receptor agonist with sedative properties and protective effects in a variety of cardiovascular diseases.
-
DescriptionCipepofol (Ciprofol), a novel 2,6-disubstituted phenol derivative, is a positive allosteric modulator and direct agonist of the GABAA receptor. Cipepofol can cause the central nerve inhibition and promote sleep based on the structural modification of Propofol (HY-B0649). Cipepofol can activate the sirtuin1 (Sirt1)/Nrf2 pathway. Cipepofol protects the heart against Isoproterenol (ISO; HY-B0468)-induced myocardial infarction by reducing cardiac oxidative stress, inflammatory response and cardiomyocyte apoptosis.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayApoptosis
-
TargetApoptosis
-
RecptorApoptosis | GABA Receptor
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1637741-58-2
-
Formula Weight204.31
-
Molecular FormulaC14H20O
-
Purity>98% (HPLC)
-
SolubilityIn Vitro:?DMSO : 100 mg/mL (489.45 mM; Ultrasonic )
-
SMILES[C@H](C)(C1=C(O)C(C(C)C)=CC=C1)C2CC2
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Ming Lu, et al. Ciprofol: A Novel Alternative to Propofol in Clinical Intravenous Anesthesia? Biomed Res Int. 2023 Jan 19:2023:7443226.?
molnova catalog
related products
-
Ginsenoside Rg6
Ginsenoside Rg6 inhibits the proliferation and induces apoptosis of human lymphoma JK cells
-
3-Methoxy-9H-Carbazo...
3-methoxy-9H-carbazole is a photosensitizer, a natural compound from Klauseneria heptaphylla and Klauseneria indica.3-methoxy-9H-carbazole has anti-breast cancer activity and induces apoptosis.
-
CDK8-IN-13
CDK8-IN-13 is a CDK8 inhibitor (IC50: 51.9 nM) with potent, selective and oral activity. CDK8-IN-13 induces apoptosis and reduces the expression of p-STAT1 S727 and p-STAT5 S726. CDK8-IN-13 exhibits anti-tumour activity.
