Cart
sales@molnova.com
Fosdevirine
CAS No. 1018450-26-4
Fosdevirine( —— )
Catalog No. M34603 CAS No. 1018450-26-4
Fosdevirine (GSK2248761) is a selective and potent non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity for the study of neurological related disorders such as late-onset epilepsy.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 2MG | 296 | Get Quote |
|
| 5MG | 459 | Get Quote |
|
| 10MG | 657 | Get Quote |
|
| 25MG | 994 | Get Quote |
|
| 50MG | 1371 | Get Quote |
|
| 500MG | Get Quote | Get Quote |
|
| 1G | Get Quote | Get Quote |
|
Biological Information
-
Product NameFosdevirine
-
NoteResearch use only, not for human use.
-
Brief DescriptionFosdevirine (GSK2248761) is a selective and potent non-nucleoside reverse transcriptase (NNRTI) inhibitor with anti-HIV activity for the study of neurological related disorders such as late-onset epilepsy.
-
DescriptionFosdevirine (GSK2248761) is is a potent, selective, non-nucleoside reverse transcriptase inhibitor (NNRTI) of human immunodeficiency virus type 1 (HIV-1) replication with low nanomolar activity in vitro. Fosdevirine shows good activity against a broad range of HIV-1 strains, including efavirenz (HY-10572)-resistant clinical isolates.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMicrobiology/Virology
-
TargetHIV
-
RecptorHIV Protease
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number1018450-26-4
-
Formula Weight413.79
-
Molecular FormulaC20H17ClN3O3P
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESP(OC)(=O)(C=1C=2C(NC1C(N)=O)=CC=C(Cl)C2)C3=CC(/C=C/C#N)=CC(C)=C3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Castellino S, et al. Central nervous system disposition and metabolism of Fosdevirine (GSK2248761), a non-nucleoside reverse transcriptase inhibitor: an LC-MS and Matrix-assisted laser desorption/ionization imaging MS investigation into central nervous system toxicity. Chem Res Toxicol. 2013 Feb 18;26(2):241-51.?
molnova catalog
related products
-
HIV-1 inhibitor-6?
3-Pyridinecarboxamide, 1,4-dihydro-1-methyl-N-(5-nitro-1,2-benzisothiazol-3-yl)-4-oxo- is a potent HIV-1 pre-mRNA selective splicing inhibitor that blocks HIV replication.
-
Atevirdine
Atevirdine is an HIV-1 reverse transcriptase inhibitor with antiviral activity for the study of the AIDS dementia complex (ADC).
-
CX 04328
CX 04328 (LEDGIN-6) is an allosteric HIV-1 integrase inhibitor that inhibits the LEDGF/p75-integrase interaction with IC50 of 1.37 uM.
