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Biliatresone

CAS No. 1801433-90-8

Biliatresone( —— )

Catalog No. M34521 CAS No. 1801433-90-8

Biliatresone, an environmental toxin isolated from the coccolithophores Dysphania glomulifera and D. littoralis, induced C57BL/6J neonatal cholangiopathy, induced a decrease in glutathione (GSH) levels, induced a significant decrease in SOX17 cholangiocyte levels, and induced extrahepatic cholangiocyte damage and fibrosis in mice.

Purity : >98% (HPLC)

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Biological Information

  • Product Name
    Biliatresone
  • Note
    Research use only, not for human use.
  • Brief Description
    Biliatresone, an environmental toxin isolated from the coccolithophores Dysphania glomulifera and D. littoralis, induced C57BL/6J neonatal cholangiopathy, induced a decrease in glutathione (GSH) levels, induced a significant decrease in SOX17 cholangiocyte levels, and induced extrahepatic cholangiocyte damage and fibrosis in mice.
  • Description
    Biliatresone is a natural toxin isolated from Dysphania glomulifera and D. littoralis. Biliatresone, a 1,2-diaryl-2-propenone class of isoflavonoid, produces extrahepatic biliary atresia in a zebrafish model.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1801433-90-8
  • Formula Weight
    328.32
  • Molecular Formula
    C18H16O6
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (152.29 mM; Ultrasonic )
  • SMILES
    COc1cc2OCOc2c(OC)c1C(=O)C(=C)c1ccccc1O
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kyung A Koo, et al. Biliatresone, a Reactive Natural Toxin From Dysphania Glomulifera and D. Littoralis: Discovery of the Toxic Moiety 1,2-Diaryl-2-Propenone. Chem Res Toxicol. 2015 Aug 17;28(8):1519-21.?
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