Cart
sales@molnova.com
(S)-ABT 102
CAS No. 808756-70-9
(S)-ABT 102( —— )
Catalog No. M34487 CAS No. 808756-70-9
N-[(1S)-5-tert-butyl-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea is a potent TRPV1 antagonist, blocking activation of TRPV1 by capsaicin with the IC50 of 123 nM.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 157 | In Stock |
|
| 5MG | 153 | In Stock |
|
| 10MG | 224 | In Stock |
|
| 25MG | 337 | In Stock |
|
| 50MG | 462 | In Stock |
|
| 100MG | 631 | In Stock |
|
| 200MG | 849 | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
-
Product Name(S)-ABT 102
-
NoteResearch use only, not for human use.
-
Brief DescriptionN-[(1S)-5-tert-butyl-2,3-dihydro-1H-inden-1-yl]-N'-1H-indazol-4-ylurea is a potent TRPV1 antagonist, blocking activation of TRPV1 by capsaicin with the IC50 of 123 nM.
-
Description(S)-ABT-102 is a TRPV1 Antagonist, with an IC50 of 123 nM. (S)-ABT-102 has analgesic activity.
-
In Vitro——
-
In Vivo——
-
Synonyms——
-
PathwayMembrane Transporter/Ion Channel
-
TargetTRP/TRPV Channel
-
RecptorTRP/TRPV Channel
-
Research Area——
-
Indication——
Chemical Information
-
CAS Number808756-70-9
-
Formula Weight348.44
-
Molecular FormulaC21H24N4O
-
Purity>98% (HPLC)
-
Solubility——
-
SMILESN(C(NC1=C2C(NN=C2)=CC=C1)=O)[C@@H]3C=4C(=CC(C(C)(C)C)=CC4)CC3
-
Chemical Name——
Shipping & Storage Information
-
Storage(-20℃)
-
ShippingWith Ice Pack
-
Stability≥ 2 years
Reference
1. Gomtsyan A, et al. Identification of (R)-1-(5-tert-butyl-2,3-dihydro-1H-inden-1-yl)-3-(1H-indazol-4-yl)urea (ABT-102) as a potent TRPV1 antagonist for pain management. J Med Chem. 2008 Feb 14;51(3):392-5.?
molnova catalog
related products
-
TRPV3 antagonist 74a
TRPV3 antagonist 74a (TRPV3 74a) is a specific TRPV3 antagonist for the study of neurological disorders.
-
GFB-8438
GFB-8438 is a potent and subtype selective inhibitor of TRPC5(IC50s of 0.18 and 0.29 μM of hTRPC5 and hTRPC4, respectively).
-
FEMA-4809
FEMA-4809, a highly potent TRPM8 receptor activator, TRPM8 is the ion channel responsible for the cool perception.
