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(R)-ZINC-3573
CAS No. 2089389-15-9
(R)-ZINC-3573( —— )
Catalog No. M34478 CAS No. 2089389-15-9
(R)-ZINC-3573 is a potent and highly selective MRGPRX2 probe that activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release.
Purity : >98% (HPLC)
COA
Datasheet
HNMR
HPLC
MSDS
Handing Instructions
| Size | Price / USD | Stock | Quantity |
| 1 mL x 10 mM in DMSO | 67 | In Stock |
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| 2MG | 37 | In Stock |
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| 5MG | 61 | In Stock |
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| 10MG | 92 | In Stock |
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| 25MG | 217 | In Stock |
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| 50MG | 319 | In Stock |
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| 100MG | 462 | In Stock |
|
| 200MG | Get Quote | In Stock |
|
| 500MG | Get Quote | In Stock |
|
| 1G | Get Quote | In Stock |
|
Biological Information
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Product Name(R)-ZINC-3573
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NoteResearch use only, not for human use.
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Brief Description(R)-ZINC-3573 is a potent and highly selective MRGPRX2 probe that activates endogenous MRGPRX2 in a human mast cell line, inducing degranulation and calcium release.
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Description(R)-ZINC-3573 is a selective Mas-related G protein-coupled receptor X2 (MRGPRX2) agonist with an EC50 value of 740 nM. (R)-ZINC-3573 can be used as a MRGPRX2 probe for the research of pain and itch.
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In Vitro——
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In Vivo——
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Synonyms——
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PathwayOthers
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TargetOther Targets
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RecptorMRGPR
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Research Area——
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Indication——
Chemical Information
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CAS Number2089389-15-9
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Formula Weight307.39
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Molecular FormulaC18H21N5
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Purity>98% (HPLC)
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SolubilityIn Vitro:?DMSO : 50 mg/mL (162.66 mM; Ultrasonic (<60°C)
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SMILESCN(C)[C@@H]1CCN(C1)c1cc(nc2ccnn12)-c1ccccc1
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Chemical Name——
Shipping & Storage Information
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Storage(-20℃)
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ShippingWith Ice Pack
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Stability≥ 2 years
Reference
1. Lansu K, et al. In silico design of novel probes for the atypical opioid receptor MRGPRX2. Nat Chem Biol. 2017 May;13(5):529-536.?
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