Home - Products - Others - Other Targets - VA-K-14 hydrochloride

VA-K-14 hydrochloride

CAS No. 1171341-19-7

VA-K-14 hydrochloride( —— )

Catalog No. M34462 CAS No. 1171341-19-7

VA-K-14 hydrochloride（VAK14 HCl） is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits TSHR stimulation by serum and monoclonal TSHR-stimulating antibodies from patients with GD and abrogates TSHR signaling.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
5MG	121	In Stock
10MG	186	In Stock
25MG	376	In Stock
50MG	600	In Stock
100MG	918	In Stock
200MG	Get Quote	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

Get Quotation Bulk Inquiry Add to Cart

Biological Information

Product Name

VA-K-14 hydrochloride
Note

Research use only, not for human use.
Brief Description

VA-K-14 hydrochloride（VAK14 HCl） is a selective thyrotropin receptor (TSHR) antagonist (IC50= 12.3 μM) that inhibits TSHR stimulation by serum and monoclonal TSHR-stimulating antibodies from patients with GD and abrogates TSHR signaling.
Description

VA-K-14 hydrochloride is a specific thyroid-stimulating hormone receptor (TSHR) antagonist (IC50= 12.3 μM).
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Others
Target

Other Targets
Recptor

TSH Receptor
Research Area

——
Indication

——

Chemical Information

CAS Number

1171341-19-7
Formula Weight

341.86
Molecular Formula

C18H16ClN3S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 50 mg/mL (146.26 mM; Ultrasonic )
SMILES

Cl.CNc1nc(cs1)-c1c([nH]c2ccccc12)-c1ccccc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Latif R, et al. TSH Receptor Signaling Abrogation by a Novel Small Molecule. Front Endocrinol (Lausanne). 2016;7:130. Published 2016 Sep 27. ?

Calculator

Molecular Weight Calculator

Dilution Calculator

Molarity Calculator

molnova catalog

related products

Vanillic Acid

Vanillic acid is used as a condiment in food,which used in wine and vinegar. It is an intermediate in the production of vanillin from ferulic acid.
Ovatodiolide

Ovatodiolide, a small molecule compound derived from fennel, has anti-inflammatory and potentially neuroprotective activity, inhibits colon tumorigenesis, and can be used in the study of neurological disorders.
Isogambogic acid

Isogambogic acid shows cytotoxic activiity against KB and drug-resistant KB-V1 cell lines.

Sign In Join Free