Upacicalcet

CAS No. 1333218-50-0

Upacicalcet( —— )

Catalog No. M34460 CAS No. 1333218-50-0

Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-sensitive receptors, thereby lowering blood levels of PTH.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
5MG 257 In Stock
10MG 380 In Stock
25MG 635 In Stock
50MG 883 In Stock
100MG 1200 In Stock
200MG Get Quote In Stock
500MG 2399 In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    Upacicalcet
  • Note
    Research use only, not for human use.
  • Brief Description
    Upacicalcet (AJT-240) is an intraventricular calcium mimetic, a SHPT available for human hemodialysis, that inhibits excessive parathyroid hormone (PTH) secretion by directly acting on parathyroid cell membrane calcium-sensitive receptors, thereby lowering blood levels of PTH.
  • Description
    Upacicalcet is an intravenous calcimimetic agent. Upacicalcet suppresses excessive parathyroid hormone (PTH) secretion, thereby lowering blood PTH levels, by acting directly on parathyroid cell membrane calcium-sensing receptors. Upacicalcet can be used for researching the disease of secondary hyperparathyroidism (SHPT).
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Calcium Channel
  • Recptor
    Calcium Channel
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1333218-50-0
  • Formula Weight
    351.76
  • Molecular Formula
    C11H14ClN3O6S
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    N(C(NC[C@@H](C(O)=O)N)=O)C1=CC(S(=O)(=O)O)=CC(Cl)=C1C
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Hoy SM. Upacicalcet: First Approval. Drugs. 2021;81(13):1593-1596. ?
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