TIBI

CAS No. 1196457-06-3

TIBI( —— )

Catalog No. M34446 CAS No. 1196457-06-3

TIBI is an ATP-competitive Rio1 inhibitor that acts in a similar manner to fungamycin and enhances the thermal stability of the enzyme.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
Size Price / USD Stock Quantity
2MG 85 In Stock
100MG Get Quote In Stock
200MG Get Quote In Stock
500MG Get Quote In Stock
1G Get Quote In Stock

Biological Information

  • Product Name
    TIBI
  • Note
    Research use only, not for human use.
  • Brief Description
    TIBI is an ATP-competitive Rio1 inhibitor that acts in a similar manner to fungamycin and enhances the thermal stability of the enzyme.
  • Description
    TIBI is a potent and ATP-competitive inhibitor of Rio1 (IC50: 0.09 μM, Ki: 0.05 μM). TIBI enhances the thermostability of the enzyme Rio1.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    Others
  • Target
    Other Targets
  • Recptor
    Others
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    1196457-06-3
  • Formula Weight
    621.72
  • Molecular Formula
    C7H2I4N2
  • Purity
    >98% (HPLC)
  • Solubility
    In Vitro:?DMSO : 50 mg/mL (80.42 mM; Ultrasonic )
  • SMILES
    IC=1C(I)=C(I)C=2NC=NC2C1I
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Kubiński K, et al. Benzimidazole inhibitors of protein kinase CK2 potently inhibit the activity of atypical protein kinase Rio1. Mol Cell Biochem. 2017 Feb;426(1-2):195-203.?
molnova catalog
related products
  • DATPT

    DATPT is a small molecule 12WLVSKF17 peptide mimetic molecule.DATPT inhibits SNX9-p47phox interactions and inhibits the production of reactive oxygen species and inflammatory cytokines.

  • ATI-2341 TFA

    ATI-2341 is an effective functionally selective allosteric agonist for the c-x-c chemokine receptor type 4 (CXCR4), which ACTS as a biased ligand in favor of G G G G G 1 activation instead of G G G G G 13.ATI-2341 activates the inhibitory heterotrimer G protein (Gi) to promote inhibition of cAMP production and induce calcium mobilization.ATI-2341 is an effective mobilization agent for myeloid polymorphonuclear neutrophils (PMNs) and hematopoietic stem and progenitor cells (HSPCs).

  • 25(27)-Ene-elephanos...

    25(27)-Ene-elephanoside H