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Home - Products - GPCR/G Protein - Adrenergic Receptor - ORM-10921

ORM-10921

CAS No. 610782-82-6

ORM-10921( —— )

Catalog No. M34365 CAS No. 610782-82-6

ORM-10921 is an α2C-adrenoceptor antagonist that has shown antipsychotic and antidepressant activity in animal studies.

Purity : >98% (HPLC)

COA Datasheet HNMR HPLC MSDS Handing Instructions
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Biological Information

  • Product Name
    ORM-10921
  • Note
    Research use only, not for human use.
  • Brief Description
    ORM-10921 is an α2C-adrenoceptor antagonist that has shown antipsychotic and antidepressant activity in animal studies.
  • Description
    ORM-10921 free base is a selective α-2C adrenergic receptor antagonist with a Ki of 1.4 nM. ORM-10921 free base displays potent antidepressant and antipsychotic-like effects.
  • In Vitro
    ——
  • In Vivo
    ——
  • Synonyms
    ——
  • Pathway
    GPCR/G Protein
  • Target
    Adrenergic Receptor
  • Recptor
    Adrenergic Receptor
  • Research Area
    ——
  • Indication
    ——

Chemical Information

  • CAS Number
    610782-82-6
  • Formula Weight
    285.38
  • Molecular Formula
    C18H23NO2
  • Purity
    >98% (HPLC)
  • Solubility
    ——
  • SMILES
    C(OC)[C@]1(C)[C@]2(C3=C(C=4C(O3)=CC=CC4)CCN2CCC1)[H]
  • Chemical Name
    ——

Shipping & Storage Information

  • Storage
    (-20℃)
  • Shipping
    With Ice Pack
  • Stability
    ≥ 2 years

Reference

1. Jukka Sallinen, et al. Pharmacological characterisation of a structurally novel α2C-adrenoceptor antagonist ORM-10921 and its effects in neuropsychiatric models. Basic Clin Pharmacol Toxicol. 2013 Oct;113(4):239-49.?
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