Omaciclovir

Research use only, not for human use.

Omaciclovir (ABT-091) is a selective herpesvirus herpesvirus replication inhibitor and a nucleoside analog with antiviral activity for the study of herpesvirus infections.

Omaciclovir (H2G) is a potent and selective inhibitor of herpesvirus replication. Omaciclovir is a nucleoside analog with antiviral activity.

Omaciclovir is a nucleoside analog with in vitro inhibitory activity against varicella-zoster virus (VZV), herpes simplex virus types 1 and 2 (HSV-1 and -2), Epstein-Barr virus, and human herpesvirus 6. Omaciclovir is also efficacious in simian varicella virus-infected monkeys.Omaciclovir shows antiviral activities against different human herpesviruses with EC50s of 0.72?±?0.1, 0.62?±?0.2, 0.015?±?0.004,0.048?±?0.023, 0.047?±?0.004, 0.035?±?0.022, and 0.016?±?0.003 μM for MRC-5 VZV-32, MRC-5 Molly, MeWo VZV-32, MeWo Molly, MeWo Emily, MeWo VZ11, and MeWo VZ30, respectively.

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Microbiology/Virology

HSV

HSV

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124265-89-0

253.26

C10H15N5O3

>98% (HPLC)

In Vitro:?DMSO : 230 mg/mL (908.16 mM; Ultrasonic )

C([C@@H](CCO)CO)N1C2=C(N=C1)C(=O)N=C(N)N2

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(-20℃)

With Ice Pack

≥ 2 years