FEMA-4809( —— )

Catalog No. M34249 CAS No. 1374760-95-8

FEMA-4809, a highly potent TRPM8 receptor activator, TRPM8 is the ion channel responsible for the cool perception.

Purity : >98% (HPLC)

COA

Datasheet

HNMR

HPLC

MSDS

Handing Instructions

Size	Price / USD	Stock	Quantity
1 mL x 10 mM in DMSO	77	In Stock
5MG	67	In Stock
10MG	112	In Stock
25MG	190	In Stock
50MG	263	In Stock
100MG	375	In Stock
200MG	514	In Stock
500MG	Get Quote	In Stock
1G	Get Quote	In Stock

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Biological Information

Product Name

FEMA-4809
Note

Research use only, not for human use.
Brief Description

FEMA-4809, a highly potent TRPM8 receptor activator, TRPM8 is the ion channel responsible for the cool perception.
Description

FEMA 4809 is a TRPM8 receptor agonist (EC50=0.2 nM) for use as a cooling agent. TRPM8 is the ion channel responsible for the cool perception.
In Vitro

——
In Vivo

——
Synonyms

——
Pathway

Membrane Transporter/Ion Channel
Target

TRP/TRPV Channel
Recptor

TRP/TRPV Channel
Research Area

——
Indication

——

Chemical Information

CAS Number

1374760-95-8
Formula Weight

327.4
Molecular Formula

C17H17N3O2S
Purity

>98% (HPLC)
Solubility

In Vitro:?DMSO : 250 mg/mL (763.59 mM; Ultrasonic )
SMILES

Cc1ccc(OCC(=O)N(Cc2cccs2)c2cc[nH]n2)cc1
Chemical Name

——

Shipping & Storage Information

Storage

(-20℃)
Shipping

With Ice Pack
Stability

≥ 2 years

Reference

1. Alain Noncovich, et al. Discovery and development of a novel class of phenoxyacetyl amides as highly potent TRPM8 agonists for use as cooling agents. Bioorg Med Chem Lett. 2017 Aug 15;27(16):3931-3938.?

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